Coagulation of Blood

IMPORTANT

Coagulation of Blood: Overview

This Topic covers sub-topics such as Coagulation of Blood, Blood Clotting Factors, Mechanism of Coagulation and, Role of Calcium in Blood Clotting

Important Questions on Coagulation of Blood

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Removal of calcium from freshly collected blood would

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Blood clotting can be prevented by the use of potassium oxalate. It is due to:

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Fibrin is ____ and ____ protein.

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When antibodies are mixed with their corresponding antigens present on the surface of animal cells, erythrocytes, or bacteria, they cross-link these objects to form visible clumps. This serological reaction is called as agglutination and is very similar to the precipitation reaction. Both reactions are specific because they depend on the specific antibody and antigen pair. Antigens involved in precipitation reaction are much smaller and more soluble than those involved in agglutination making the latter reaction easily detectable. Which of the following options is best suited to make the precipitation reaction more easily detectable?

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Study the following table and pick up the correct combinations.

SNo Clotting Name of the factor Function
I XII Hageman factor Activates cascade reactions of intrinsic pathway
II XIII Fibrin stabilising factor Stabilises and strengthens the clot
III III Prothrombin Prevents clotting of blood
IV I Fibrinogen Forms serum on the blood clot

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Which of the following is an anticoagulant and checks blood coagulation in blood vessels?

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Blood clotting occurs with the help of

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Removal of calcium from freshly collected blood would 

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Which of the following prevents the conversion of prothrombin in an undamaged blood vessel?

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Which of the following is not useful in blood clotting.

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Human blood clotting VII is used to treat

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Blood protein directly involved in blood coagulation is

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For clotting of blood, which of the following is necessary ?

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Important ion for blood clotting is

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Which cations play an important role in the formation of a coagulum of fibrin proteins?

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Cattle fed with spoilt hay of sweet clover which contains dicumarol

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Fibrinogen is synthesised in

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Which of the following is an incorrect statement with respect to the functions of minerals?

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______ serves as a cofactor for enzymes that catalyzes carboxylation and therefore activation of clotting factors like prothrombin.

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Mechanism of blood clotting is given below:

An injury or a trauma stimulates the platelets in the blood to release certain factors which activate the mechanism of coagulation. An enzyme complex, ______P_______ is formed by a series of linked enzymic reactions (______Q_______process) involving a number of factors present in the plasma in an inactive state. This enzyme complex is required for formation of______R_______. _____S_______ ions play a very important role in clotting.

Identify the correct option that represents P, Q, R, and S.